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NBA Picks April 6, 2025: Spurs vs Trail Blazers Prediction & Best Bets

NBA Picks April 6, 2025: Spurs vs Trail Blazers Prediction & Best Bets

San Antonio Spurs vs Portland Trail Blazers – 6:00 PM ET – Moda Center (BlazerVision)

Spread: Trail Blazers -3
Over/Under: 228.5
Moneyline: Blazers -145, Spurs +125


Game Preview:

Two rebuilding squads square off in the Pacific Northwest on Sunday night as the Spurs visit the Blazers in a game that offers more betting value than playoff implications. Both teams are out of the postseason hunt, but young players are getting extended run — and these rosters are still playing hard despite the standings.

San Antonio is just 1-6 in its last seven games but has been a surprisingly strong bet against the spread. The Spurs have covered in 7 of their last 10 and recently pushed the Cavaliers to the wire as 11-point dogs. With Victor Wembanyama shut down for the year, the Spurs have leaned on Devin Vassell, Keldon Johnson, and rookie Stephon Castle, who continues to flash in expanded minutes. San Antonio still ranks near league average in scoring (114.2 PPG), and they’ve covered in 5 of their last 6 road games vs losing teams from the Northwest Division.

Portland, meanwhile, continues to grind despite missing several key pieces. Deandre Ayton, Jerami Grant, and Robert Williams are all out, while Anfernee Simons is questionable. That leaves Shaedon Sharpe and Deni Avdija to do the heavy lifting — and both have shown flashes. Portland is 4-1 SU in its last five home games vs teams with a losing record and has covered 4 straight against the Spurs after a loss. They’ve also hit the Over in 4 straight home games as a favorite following a road loss, which aligns with today’s setup.


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Best Bet: Spurs +3

Neither team is at full strength, and both are out of the playoff race — but the Spurs have been the more consistent bet. They’ve covered in 7 of 10 overall and match up well with a thin Portland squad missing its top interior presence (Ayton). The Spurs have also won 6 of the last 7 outright against Portland, making them a strong underdog value side. Take the points in what should be a close, fast-paced battle between two developmental rosters.


Top Player Prop: Shaedon Sharpe Over 19.5 Points

With Ayton, Grant, and possibly Simons out, Sharpe should take on a massive scoring role. He’s posted 20+ in 3 of his last 4 when getting 15+ shot attempts, and the Spurs have struggled all year to contain explosive guards. In a matchup with minimal resistance and plenty of pace, Sharpe’s volume will be high — making him one of the best NBA player props today on the board.


Spurs vs Trail Blazers Betting Trends:

  • Spurs are 6-1 SU in the last 7 meetings

  • Spurs are 5-1 ATS in their last 6 road games vs NW Division teams after a loss

  • Blazers are 4-0 ATS in their last 4 at home vs losing teams

  • Blazers are 0-5 ATS in their last 5 as home favorites after a road loss

  • Over is 4-0 in Portland’s last 4 games as a home favorite following a loss


Spurs vs Trail Blazers FAQ

Who is favored in Spurs vs Trail Blazers tonight?
The Portland Trail Blazers are 3-point favorites over the San Antonio Spurs.

What time is Spurs vs Blazers on April 6, 2025?
Tip-off is at 6:00 PM ET at Moda Center in Portland.

What is the Over/Under for Spurs vs Trail Blazers?
The total is currently set at 228.5 points.

Who is out for the Spurs and Trail Blazers?
The Spurs are without Victor Wembanyama, Jeremy Sochan, and De’Aaron Fox. The Blazers are missing Deandre Ayton, Jerami Grant, and Robert Williams III. Anfernee Simons is questionable.

What’s the best NBA player prop for this game?
Shaedon Sharpe Over 19.5 points is one of the top NBA prop picks today due to increased usage and favorable matchup.

Which team has the ATS edge?
The Spurs are 7-3 ATS in their last 10 games overall, while the Blazers have failed to cover in 5 straight as home favorites after a road loss.



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