Cincinnati Reds vs Milwaukee Brewers – 2:10 PM ET – American Family Field (Tele)

Starting Pitchers: Carson Spiers (CIN) vs Chandler Patrick (MIL)
Moneyline: Brewers -148, Reds +124
Over/Under: 8.5

Game Preview:

The Cincinnati Reds and Milwaukee Brewers close out their early-season divisional series Sunday at American Family Field, with the series tied 1-1 after the Reds exploded for 11 runs in Saturday’s 11-7 win. Both clubs are off to uneven starts in 2025, though each has shown flashes of upside through their first nine games.

Milwaukee is 4-5 on the season and enters this game having dropped 5 of its last 7 overall. Despite their early struggles, the Brewers have been competitive at home and are 4-2 in their last 6 home games vs the Reds. The offense is led by Sal Frelick (.394 AVG, 13 hits), while Brice Turang and Rhys Hoskins have combined for 10 runs and 11 RBIs. However, pitching has been an issue — Milwaukee ranks in the bottom 5 in team ERA (6.41) and WHIP (1.39), and they’ve allowed 7+ runs in four of their last six games.

Chandler Patrick will make his second start of the year for Milwaukee. He was efficient in his debut, tossing 4.2 scoreless innings against the Royals while allowing just 3 hits. However, Patrick hasn’t worked deep into games and will need strong bullpen support in this one. Milwaukee’s relief corps has been inconsistent, with a blown save and a bullpen ERA over 5.00 through the first two series.

Cincinnati enters at 3-6 and snapped a four-game skid with their win on Saturday. The Reds offense finally broke out after scoring just 9 total runs across their previous 5 games. Elly De La Cruz continues to be a spark plug (9 hits, 10 RBIs, 7 runs), while TJ Friedl leads the team with a .294 average and 10 hits. Cincinnati's pitching has been far more reliable than expected — they rank 4th in team ERA (2.85) and 1st in WHIP (0.99).

Carson Spiers takes the mound for the Reds after delivering a strong season debut: 6 innings, 1 ER in a win over Texas. He was erratic in 2024 (5.46 ERA), but early returns suggest he may be trending upward. Spiers did get lit up by the Brewers last year (8 ER in 5 IP), but Milwaukee’s current form is less threatening than the 2024 version. With both starters still unproven and both bullpens shaky, this is a matchup where value lies with the underdog.

Best Bet: Reds +124 (Moneyline)

The Brewers may be favored due to their recent head-to-head success and home field, but the Reds have shown more consistency on the mound and finally got their bats going Saturday. Spiers looked sharp in his 2025 debut, and Cincinnati’s bullpen has been far more dependable than Milwaukee’s. With the plus-money price and both starters relatively untested, this is a great MLB best bet today on the road underdog with better pitching form and upside.

Check out these articles for winning picks:

Top Player Prop: Elly De La Cruz Over 1.5 Total Bases (+120)

De La Cruz has been the Reds’ most electric hitter early in the season and already has 10 RBIs through 9 games. He had multiple hits on Saturday and is seeing the ball well. With Patrick likely to work fewer than five innings, De La Cruz should get good looks against Milwaukee’s shaky bullpen. In a game with sneaky offensive potential, Elly over 1.5 total bases is one of the most actionable MLB player props today.

Reds vs Brewers Betting Trends:

Brewers are 7-3 SU in last 10 vs Reds
Reds are 4-1 ATS in last 5 as road underdogs vs NL Central opponents
Brewers are 1-4 SU in last 5 after a home loss
Reds are 0-7 ATS in last 7 Sunday games vs losing teams
Under is 7-0 in Reds’ last 7 day games vs NL Central opponents
Under is 4-1 in Brewers’ last 5 vs NL Central

Reds vs Brewers FAQ

Who is favored in Reds vs Brewers on April 6, 2025?
The Milwaukee Brewers are -148 home favorites over the Cincinnati Reds.

What time is Reds vs Brewers today?
First pitch is set for 2:10 PM ET at American Family Field in Milwaukee.

What is the Over/Under for Reds vs Brewers?
The total is 8.5 runs — with recent trends leaning toward the Under.

Who are the starting pitchers?
Carson Spiers (Reds) vs Chandler Patrick (Brewers). Both are making their second start of the 2025 season.

What’s the best MLB player prop in this game?
Elly De La Cruz Over 1.5 total bases is a top prop target given his form and the Brewers’ bullpen weakness.

Which team has the edge today?
The Reds hold the edge in pitching (2.85 ERA vs 6.41), and Spiers has shown better command than Patrick. At +124, Cincinnati has strong underdog value.

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