Pittsburgh vs Louisville Prediction NCAAF Picks 10/14

Pittsburgh vs Louisville Prediction NCAAF Picks 10/14

© Jamie Rhodes-USA TODAY Sports


Louisville vs. Pittsburgh: College Football Preview

The No. 14 Louisville Cardinals (6-0, 3-0 ACC) are set to face the struggling Pittsburgh Panthers (1-4, 0-2 ACC) in what could be a defining ACC matchup. The game is scheduled for 3:30 PM on October 14, 2023, at Acrisure Stadium in Pittsburgh, PA, with coverage on CW NETWORK. Louisville enters this game as favorites with a line of -7.5 points.


Crucial Matchup Analysis

Louisville's Impressive Streak

The Louisville Cardinals have been on an impressive winning streak, having won seven straight games dating back to 2022. Their success is a testament to the turnaround under first-year coach Jeff Brohm. Notably, they secured a tough road win at N.C. State and recently upset Notre Dame, propelling them up the rankings.

This strong momentum, combined with their dynamic offense, positions Louisville as a formidable opponent for the struggling Panthers.


Pittsburgh's Offensive Line Woes

The Pittsburgh Panthers have struggled with their offensive line, leading to challenges in protecting their quarterbacks. Injuries and frequent changes in offensive line combinations have compounded their issues. To make matters more challenging, they are facing a Louisville defense that has been producing turnovers and stifling opposing offenses.

The matchup to watch is Pitt's offensive line against Louisville's defensive front, as it may determine the effectiveness of Pittsburgh's offense.



As the game approaches, it's clear that Louisville's impressive form and offensive firepower give them a significant advantage in this matchup. The Cardinals are not only poised to win but also to cover the -7.5 points spread.

Pittsburgh's struggles on both sides of the ball, coupled with their difficulties in protecting their quarterback, could play into Louisville's hands. Look for Louisville to capitalize on turnovers and make the most of scoring opportunities.

The -7.5 points spread is a reasonable bet in favor of Louisville, as they are likely to control the game and secure a comfortable victory against a struggling Pittsburgh team.


Prediction: Louisville -7.5 

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