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Minnesota Twins vs San Diego Padres Prediction, Odds & Best Bet - August 21, 2026

KINGPIN Updated Aug 22, 2026 at 12:00 AM EDT 6 min read

Minnesota Twins vs San Diego Padres Prediction, Odds & Best Bet - August 21, 2026

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MATCHUP

Minnesota Twins vs San Diego Padres

final

AwayMinnesota Twins63-66SP: Connor Prielipp

August 21, 20269:41 PM EDTPetco Park

HomeSan Diego Padres69-60SP: Randy Vásquez

Weather: Condition: Partly Cloudy · Temp: 79 · Wind: 6 mph, L To R

LIVE MARKET SNAPSHOT

Minnesota Twins vs San Diego Padres odds

As of Aug 22, 2026 at 12:00 AM EDT

Moneyline

Minnesota Twins

+6500FanDuel

San Diego Padres

-3800DraftKings

Run Line

Minnesota Twins3.5

+1200FanDuel

San Diego Padres-3.5

-425Fanatics

Minnesota Twins4.5

-320FanDuel

San Diego Padres-4.5

+290MyBookie

Total

Over8.5

+1200FanDuel

Under8.5

-122FanDuel

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2260-1690-26 · 80.9u · 80906 simulated

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