San Francisco 49ers vs Los Angeles Rams Prediction, Pick and Preview, October 3 (10/3) NFL

San Francisco 49ers vs Los Angeles Rams Prediction, Pick and Preview, October 3 (10/3) NFL



Time 8:15 p.m. EST
Rams money line +100
Rams spread +1.5 (-110)
49ers money line -120
49ers spread -1.5 (-110)
Over / under 42.5


2022 season stats

  Los Angeles Rams San Francisco 49ers
Record 2-1 1-2
Road / home record 1-0 1-0
Points per game 20.3 15.7
Points allowed per game 23.3 12.3
O/U 1-2 0-3
Pass yards per game 253.0 186.0
Rush yards per game 72.7 151.0
Total yards per game 326.5 337.5
Total yards allowed per game 362.5 246.0



The San Francisco 49ers will host the Los Angeles Rams on Monday Night at the Levi's Stadium. These teams faced each other twice last season in LA and they tied 1-1 but the 49ers covered the spread in both games.


Los Angeles Rams

The Rams were dominated by Buffalo in the kick off game of the season but they won the next 2 games against the Falcons and the Cardinals. The Rams are posting the third-lowest rushing average in the NFL at 72.3 yards per game, easily the lowest mark in McVay's six seasons, while averaging a pitiful 3.4 yards per run. Although Cam Akers and Darrell Henderson are having trouble, McVay has still found ways to exploit the fundamental components of the running game.

The Defense survived quite an onslaught on Sunday afternoon defending 58 passing plays from Arizona's Kyler Murray, who is notoriously hard to defend because of his ability to throw and run.. Aaron Donald has one sack in his past five games against San Francisco after having 10 1/2 the previous six meetings.


San Francisco 49ers

The 49ers get here with a 2-1 record and lost their last game on the road against the Denver Broncos 11-10. Garappolo looked rusty and missed on a few chances at big plays in the first half, then turned it over twice in the second half, as well as stepping out of the end zone for a safety in the 11-10 loss to Denver. Brandon Ayiuk leads the team with 142 yards received and 1 touchdown while Jeff Wilson Jr. has 181 rushing yards in 39 carries.

The Defense has been pretty tough allowin only 12.3 points per game, 167 pass yards and 78 rushing yards. All-Pro left tackle Trent Williams is out with a high ankle sprain and will likely be replaced by Colton McKivitz.



LA Rams are 0-5 ATS in their last 5 games against San Francisco.

LA Rams are 1-6 SU in their last 7 games against San Francisco.

LA Rams are 6-0 SU in their last 6 games on the road.

The total has gone UNDER in 7 of LA Rams' last 9 games when playing on the road against San Francisco.

The total has gone UNDER in 6 of San Francisco's last 6 games.

San Francisco are 10-5 SU in their last 15 games.

The total has gone UNDER in 4 of San Francisco's last 5 games against LA Rams.



The Rams have managed to win their last 2 games but haven't looked like the last season. In their previous six regular-season meetings, the Niners have prevailed over the Rams, including a Week 18 game last January that helped them advance to the playoffs but the offense has been awful and with Donald and the Rams defense they'll continue to struggle. San Francisco's defense has been pretty tough as well so expect a low scoring game on Monday Night. Take the under.

PICK: Under 42.5 (-110)

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