Los Angeles Rams vs Buffalo Bills Prediction, Pick and Preview, September 8 (9/8) NFL

Los Angeles Rams vs Buffalo Bills Prediction, Pick and Preview, September 8 (9/8) NFL



Time 8:20 p.m. EST
Bills money line -123
Bills spread -2.5 (-110)
Rams money line +115
Rams spread +2.5 (-110)
Over / under 52.5


2022 season stats

  Buffalo Bills Los Angeles Rams
Record 0-0 0-0
Road / home record 0-0 0-0
Points per game 0-0 0-0
Points allowed per game 0-0 0-0
Pass yards per game 0 0
Rush yards per game 0 0
Total yards per game 0 0
Total yards allowed per game 0 0
Turnover ratio 0 0



The reigning champions Los Angeles Rams opens the 2022 regular season Thursday against the Buffalo Bills at the SoFi Stadium in LA. These teams haven't faced each other since 2020 season where the Bills beat the Rams 35-32 in Buffalo.


Buffalo Bills

The Bills enter this season as the favorites to win the super bowl and they were just seconds away from advancing to the conference finals last season but let the Chiefs to tie the game and beat them in overtime. Buffalo had an 11-6 record last season and were 5-3 on the road.

Offensively, the team averaged 28.4 points per game recording 4,284 passing yards and 2,209 rushing yards. This offense is expected to be one of the best this year leaded by their star quarterback Josh Allen who registered 4,407 passing yds, 36 touchdowns and 15 interceptions with a 63.3% in passes completed ranking 6th in the NFL. He was also the 3rd best quarterback in rushing yards with 763. His best arms are the receivers Devin Singletary, Stefon Diggs, Gabe Davis and Dawson Knox but they just added the rookie James Cook one of the stars from the Georgia Bulldogs.

Defensively, the team ranked #1 in the NFL allowing an average of 16.11 points per game last season and they just signed the defensive star Von Miller who's the current sack leader, so this is going to be a tougher defense this year.


Los Angeles Rams

The reigning champs had a 12-5 overall record and 5-3 at home in the regular season last year and beat the Cincinnati Bengals 23-20 in the Super Bowl. The team lost several players like Von Miller, Sony Michel, Andrew Withworth and Robert Woods, but they still have plenty of talent to make the difference and defend the championship.

Offensively, the team averaged 27.1 points per game #12 in the nation and recorded 4,642 passing yards and 1,683 rushing yards and ranked #2 in yards per play last season. The quarterback Matt Stafford will be leading the team to another championship. He had 4,886 passing yards #3 in the NFL, 41 td's and 17 interceptions. 

Defensively, this team allowed an average of  21.9 points per game last season. They traded Von Miller to the Bills but acquired the veteran Bobby Wagner from the Seahawks. The defense is not expected to lose strenght as they still have the best defensive player in the league Aaron Donald and Jalen Ramsey as well.



Buffalo are 5-1 SU in their last 6 games.

Buffalo are 4-1 ATS in their last 5 games against LA Rams.

Buffalo are 4-1 SU in their last 5 games against LA Rams.

LA Rams are 9-1 SU in their last 10 games.

The total has gone OVER in 8 of LA Rams' last 9 games against Buffalo.



The Rams will be strong contenders to win the championship again this year, but the Bills are the favorites to win it all and honestly, if they had held the lead in those last 13 seconds of the fourth quarter against the Chiefs, I think they would beat the Bengals and possibly the Rams in the Super Bowl. The Bills' defense is the best in the league and they have a very complete quarterback who can be a nightmare for any defense. The Bills are 5-2 in the last 7 head-to-head games against the Rams and the average score is 31.8-22.5, so go with the Bills to take the win in the 2022 NFL kickoff game on Thursday night.

PICK: Bills ML (-123)

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