Denver Broncos vs San Francisco 49ers Prediction, Pick and Preview, September 25 (9/25) NFL
- Lm Tipster
- Sep 25, 2022, 6:42:29 AM
Odds
| Time | 8:20 p.m. EST |
| Broncos money line | +105 |
| Broncos spread | +1.5 (-110) |
| 49ers money line | -125 |
| 49ers spread | -1.5 (-110) |
| Over / under | 45 |
2022 season stats
| Denver Broncos | San Francisco 49ers | |
| Record | 1-1 | 1-1 |
| Road / home record | 0-1 | 1-0 |
| O/U | 0-2 | 0-2 |
| Points per game | 16.0 | 18.5 |
| Points allowed per game | 13.0 | 13.0 |
| Pass yards per game | 174.0 | 279.5 |
| Rush yards per game | 182.5 | 126.0 |
| Total yards per game | 356.5 | 405.5 |
| Total yards allowed per game | 226.5 | 264.0 |
Preview
The San Francisco 49ers will visit the Denver Broncos at the Empower Field at Mile High to play on Sunday Night Football. These teams haven't faced each other since 2018 season where the 49ers beat the Broncos 20-14 in San Francisco.
Denver Broncos
The Broncos had a bad season last year ending with a 7-10 record and 3-5 on the road led by Teddy Bridgewater who's now the backup quarterback for the Dolphins. Last week they got their first victory on the season after beating the Houston Texans 16-9.
Offensively, the team was 13th in rushing offense with 119.1 yards per game and 19th in the league in passing offense with 211.4 yards per game. With 19.7 points per game, Denver's offense ranked 23rd in the league. This year the offense received a big boost after acquiring Russell Wilson who had 3,113 yds, 25 td and 7.8 yds average per play while only 6 interceptions. They had one of the finest running games in the league, headed by Melvin Gordon III and Javonte Williams, who both rushed for over 900 yards. Courtland Sutton had 776 yards.
Defensively, the team ranked #3 in the NFL allowing an average of 18.9 points per game last season. This is a tough defense that is expected to continue to dominate this season.
San Francisco 49ers
The 49ers also had their first win of the season after beating the Seattle Seahawks 27-7 at home. After the shock of losing starting quarterback Trey Lance to a season-ending injury subsided, Jimmy Garoppolo's return to the San Francisco 49ers' starting lineup. He threw a touchdown pass on his first full drive after replacing Lance and ran for another score. Garoppolo went 13 for 21 for 154 yards and the TD.
Offensively, the team is averaging 18.5 points per game. Brandon Ayiuk leads the team in yards received with 103 in 7 receptions while Wilson Jr. has 106 rushing yards in 27 carries. George Kittle will make his first start of the season.
Defensively, this team has been pretty good and are allowing an average of 13.0 points per game so far.
BETTING TRENDS
San Francisco are 10-4 SU in their last 14 games.
San Francisco are 6-3 ATS in their last 9 games against Denver.
San Francisco are 6-3 SU in their last 9 games against Denver.
The total has gone UNDER in 6 of San Francisco's last 7 games on the road.
Denver are 1-5 ATS in their last 6 games.
The total has gone UNDER in 10 of Denver's last 13 games.
Denver are 1-5 SU in their last 6 games.
The total has gone UNDER in 4 of Denver's last 6 games against San Francisco.
Prediction
Wilson and company got their first win of the season but continued to struggle offensively as they scored only 16 points but the defense has been very solid and are allowing 13 ppg. The 49ers are now leaded by Jimmy Garappolo who looked like he never left in the last game and will have the best arm back in George Kittle. This should be a close game as both defenses have been great so the best play is the under.
PICK: Under 45 (-110)
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