Pittsburgh Pirates vs Chicago Cubs Prediction, Pick and Preview, June 22 (6/22): MLB

Pittsburgh Pirates vs Chicago Cubs Prediction, Pick and Preview, June 22 (6/22): MLB

Credit: photo by Charles LeClaire-USA TODAY Sports



Time 7:05 p.m. EST
Cubs money line -105
Cubs run line +1.5 (-185)
Pirates money line -115
Pirates run line -1.5 (+160)
Over / under 9


Key stats

  Chicago Cubs Pittsburgh Pirates
Record 25-43 28-39
Road / home record 12-18 16-19
Last 10 record 2-8 4-6
Streak L2 W2
Over / under record 33-32-3 27-35-3
Runs / game 4.23 3.39
Runs allowed / game 5.22 5.03



The Chicago Cubs and the Pittsburgh Pirates will play the 3rd game of the series at the PNC Park on Wednesday. The Pirates outscored the Cubs again 7-1 on tuesday to take the lead 2-0 on the series and they're now 7-4 against them so far this season.

Chicago Cubs

The Cubs get here with a 25-43 record and have lost 8 their last 10 games. The team is averaging 4.2 runs per game with a .242 at bat while allowing 5.2 runs. Wilson Contreras is leading the team with 12 home runs and 27 RBI while Happ has the better batting average with .284.

Keegan Thompson leads the pitching staff with a 3.27 ERA, 48 strikeouts and 6 wins recorded for the Cubs.

Probable Pitcher:

Keegan Thompson (6-2, 3.27 ERA) will be on the mound for the Cubs in the 3rd game of the series. Thompson allowed two hits and two walks in six scoreless innings against Atlanta on Friday. He sat out nine and did not consider the decision. He has a record of 2-0 with an ERA of 1.76 and 14 strikeouts in 5 appearances against the Pirates in his career.

Pittsburgh Pirates

The Pirates get to this game with a 28-39 record and have won 4 of their last 6 games. The team is averaging 3.4 runs and allowing 5 runs per game. Ke'Bryan Hayes is batting for .270 AVG and has 21 RBI. Bryan Reynolds leads in home runs with 11.

JT Brubaker (1-7) pitched six scoreless innings for his first win of the season. He leads the team with a 4.11 ERA, 70 strikeouts and 1 win.

Probable Pitcher: 

Jerad Eickhoff (0-0, 0.00 ERA) will take the mound in the 3rd game of the series for the Pirates. Eickhoff will be joining the rotation as a replacement for Zach Thompson, who was placed on the 15-day injured list. Eickhoff has a 4.84 ERA, 1.08 WHIP, and 47:15 K:BB ratio in 13 appearances (six starts) for Indianapolis this season.


Chi Cubs are 3-7 SU in their last 10 games against Pittsburgh.

Chi Cubs are 0-7 SU in their last 7 games on the road.

Pittsburgh are 4-11 SU in their last 15 games.

The total has gone UNDER in 8 of Pittsburgh's last 11 games against Chi Cubs.


The Pirates dominated the Cubs again beating them 7-1 on Tuesday and they're 7-4 against them this season. The Chicago Cubs continue to struggle offensively as they have scored only 2 run in their last 3 games. They might have chances to stop the Pirates offense with Keegan Thompson on the mound who has dominated the Pirates in his career while the Pirates are calling a rookie to start this game. I'll give it a shot with the Cubs as Thompson should slow down the Pirates offense.

PICK: Cubs ML (-105)

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