MLB Predictions, Best Bets and Player Props for Saturday, April 26, 2025

Toronto Blue Jays @ New York Yankees (1:05 PM) – The Yankees (15-11) host the Blue Jays (13-13) at Yankee Stadium. New York’s ace Max Fried (4-0, 1.42 ERA) takes on Toronto’s Kevin Gausman (2-2, 3.16 ERA). The Yankees are short-money favorites (around -180) and the total sits near 9 runs. New York’s offense, led by Aaron Judge and Anthony Rizzo, is clicking on all cylinders, and Judge (7 HR in 26 games) is a major threat. Toronto has power (Vladimir Guerrero Jr., Bo Bichette), but Fried has been dominant. We like the Yankees to win and cover.

• Best Bet: Yankees moneyline.

• Top Prop: Aaron Judge anytime home run.

Baltimore Orioles @ Detroit Tigers (Game 1, 1:10 PM) – Detroit (15-10) hosts a rain-delayed opener versus Baltimore (10-14) in a doubleheader. Casey Mize (Detroit) has been outstanding early (W-L 3-1, 2.22 ERA) while the Orioles turn to rookie Brandon Young, making only his second big-league start. Detroit is a slight favorite (Tigers around -125) with a moderate total (about 8.5 runs). The Tigers’ lineup (Spencer Torkelson, Riley Greene, Kerry Carpenter) should handle Young’s inexperience. Expect Detroit to dominate Game 1 with a solid offense outing.

• Best Bet: Tigers moneyline.

• Top Prop: Riley Greene over 0.5 RBIs.

Boston Red Sox @ Cleveland Guardians (Game 1, 1:10 PM) – In Cleveland, the Guardians (14-13) host the Red Sox (14-13) in the opener of a twinbill. Pitchers are TBD, but both clubs are evenly matched in records. The line makes Cleveland slight favorites and the total is around 8 runs. Cleveland’s lineup (José Ramírez, Steven Kwan, Andrés Giménez) is traditionally deep, and Boston still looks for consistency despite new ace Walker Buehler on the staff. The Guardians should take advantage of the home start and shy Red Sox bats.

• Best Bet: Guardians moneyline.

• Top Prop: José Ramírez 1+ RBIs.

Los Angeles Angels @ Minnesota Twins (2:10 PM) – The Twins (12-13) welcome the Angels (6-18) at Target Field. Lefty Simeon Woods Richardson starts for Minnesota, and LAA counters with Yusei Kikuchi. Minnesota are narrow favorites (about -122) and the O/U is roughly 9 runs. The Angels have struggled to score, while the Twins sports a stout offense featuring Jorge Polanco and Carlos Correa. Take the Twins and bet overs if the game unlocks.

• Best Bet: Twins moneyline.

• Top Prop: Jorge Polanco over 0.5 RBIs.

Milwaukee Brewers @ St. Louis Cardinals (2:15 PM) – The Cardinals (11-15) host Milwaukee (13-13). St. Louis sends Sonny Gray to the mound versus Brewers’ Quinn Priester. The Cards are firm home favorites (around -155) and the total is about 9 runs. Milwaukee’s lineup (Nick Castellanos, William Contreras) is talented, but St. Louis has the pitching edge and the home crowd. Look for St. Louis to win a relatively low-scoring contest.

• Best Bet: Cardinals moneyline.

• Top Prop: Paul Goldschmidt 1+ RBIs.

Cincinnati Reds @ Colorado Rockies (3:10 PM) – In Denver, the surging Reds (12-13) face the struggling Rockies (4-21). Cincinnati’s flamethrower Hunter Greene (4-2, 1.75 ERA) faces Colorado’s Antonio Senzatela. The Reds are heavy road favorites (around -190) and Coors Park usually produces runs, with the total near 10. Cincinnati’s firepower (Elly De La Cruz, TJ Friedl, Matt McLain) should feast on Senzatela. Expect a lopsided Reds win in the Rockies’ ballpark.

• Best Bet: Reds moneyline.

• Top Prop: Elly De La Cruz 1+ extra-base hits.

New York Mets @ Washington Nationals (4:05 PM) – The red-hot Mets (18-8) visit Washington (12-14). New York’s closer-turned-starter Clay Holmes goes against Brad Lord. The Mets are clear favorites (~-175) with the total around 9. Washington’s offense is weak (scoring below league average) and they’ll struggle against Holmes. The Mets lineup (Pete Alonso, Francisco Lindor, Brandon Nimmo) should carry them to an easy road win.

• Best Bet: Mets moneyline.

• Top Prop: Pete Alonso anytime home run.

Philadelphia Phillies @ Chicago Cubs (4:05 PM) – At Wrigley Field, the Cubs (17-10) host the Phillies (13-12). Phillies’ Jesus Luzardo opposes Ben Brown of Chicago. The Cubs are slight favorites (about -110) and the total is in the high-8s. Both lineups are fairly even, but Chicago’s home hitters (Ian Happ, Seiya Suzuki, William Contreras) have been in fine form. We’ll lean Cubs in a close one.

• Best Bet: Cubs moneyline.

• Top Prop: William Contreras 1+ RBIs.

Texas Rangers @ San Francisco Giants (4:05 PM) – The Giants (17-11) play host to Texas (14-11) at Oracle Park. Robbie Ray starts for SF against Tyler Mahle of Texas. Odds are tight (Giants slight favorites around -115) and the total is high (around 9.5) in this hitter-friendly park. San Francisco’s offense (Michael Conforto, Brandon Belt’s legacy here) combined with Ray’s quality could overwhelm the Rangers. Pick the Giants to stay hot at home.

• Best Bet: Giants moneyline.

• Top Prop: Wilmer Flores 1+ hits.

Chicago White Sox @ Oakland Athletics (4:05 PM) – In Oakland, the A’s (12-13) host the struggling Sox (6-19). Lefty Jeffrey Springs starts for the A’s against Chicago’s Jonathan Cannon. Oakland are big favorites (around -225) and the total is low (around 8). Chicago’s lineup is anemic, so expect the A’s, with key bats like Mitchy and Mark Canha, to cruise in this one.

• Best Bet: Athletics moneyline.

• Top Prop: Mark Canha over 1.5 total bases.

Boston Red Sox @ Cleveland Guardians (Game 2, 6:10 PM) – The nightcap in Cleveland features Walker Buehler (Boston) vs newcomer Doug Nikhazy (Cleveland). Buehler, acquired from LA, makes his Red Sox debut. The Guardians are slight home favorites and the total is modest (~8 runs). Boston’s offense (especially Rafael Devers and Xander Bogaerts) should get a boost from Buehler’s pitching and Red Sox fans will rally. Lean Red Sox on the road for the win.

• Best Bet: Red Sox moneyline.

• Top Prop: Rafael Devers 1+ RBIs.

Baltimore Orioles @ Detroit Tigers (Game 2, 6:10 PM) – In Game 2, Detroit likely again fields an ace (possibly Michael Fulmer) against Baltimore’s Austin Wells or another prospect. The Tigers again open as home favorites with a similar total (~8.5). Detroit’s bats (Spencer Torkelson, Riley Greene) should remain too powerful.

• Best Bet: Tigers moneyline.

• Top Prop: Spencer Torkelson anytime home run.

Houston Astros @ Kansas City Royals (7:10 PM) – The Astros (13-13) visit the Royals (13-14). Framber Valdez starts for Houston against KC’s Michael Wacha. Houston are around -135 favorites, total low (~8). Valdez’s steady arm should stifle KC, and Houston’s lineup (José Altuve, Alex Bregman, Yordan Álvarez) will capitalize. Expect an Astros win with KC struggling offensively.

• Best Bet: Astros moneyline.

• Top Prop: Yordan Álvarez 1+ RBIs.

Atlanta Braves @ Arizona Diamondbacks (8:10 PM) – The Diamondbacks (14-11) host Atlanta (10-15) in Phoenix. Merrill Kelly toes the rubber for Arizona vs Atlanta’s Grant Holmes. Arizona are slight favorites (about -120) with the total near 8.5. The D-backs’ offense (Ketel Marte’s replacement, Eduardo Escobar, Christian Walker) and Kelly’s pitching should edge out the Braves, who are still finding consistency.

• Best Bet: Diamondbacks moneyline.

• Top Prop: Ezequiel Tovar 1+ hits.

Tampa Bay Rays @ San Diego Padres (8:40 PM) – In San Diego, the Padres (17-10) host Tampa Bay (11-14). Dylan Cease starts for SD against Ryan Pepiot of the Rays. Padres are heavy favorites (-155) and the total is high (~9.5). With power bats like Manny Machado and Fernando Tatis Jr., and a strong home park, San Diego should handle Tampa easily.

• Best Bet: Padres moneyline.

• Top Prop: Fernando Tatis Jr. anytime home run.

Pittsburgh Pirates @ Los Angeles Dodgers (9:10 PM) – Los Angeles (16-9) welcomes Pittsburgh (10-14). Dodgers rookie Roki Sasaki, making one of his first starts in the majors, squares off with Mitch Keller. LA are extreme favorites (-265) and the total is about 10 thanks to Dodger Stadium’s offense. Mookie Betts and the Dodgers lineup should feast, handing the Pirates another loss.

• Best Bet: Dodgers moneyline.

• Top Prop: Mookie Betts 1+ hits.

Miami Marlins @ Seattle Mariners (9:40 PM) – Seattle (15-11) hosts Miami (11-14). Luis Castillo pitches for Seattle against Miami’s Connor Gillispie. Seattle are strong favorites (-230) and the total is moderate (~8.5). The Mariners, with Julio Rodríguez and Mitch Haniger leading the way, should easily outgun the Marlins.

• Best Bet: Mariners moneyline.

• Top Prop: Julio Rodríguez anytime home run.

FAQ

Q: What are the MLB best bets today?
A: Our analysis highlights top plays for April 26. Key MLB best bets include favorites like the Yankees, Twins, Cardinals, Mets, Cubs, Giants, A’s, Cubs, Dodgers, and Mariners on the moneyline. Also target strong underdogs if value, such as X-over totals in matchups like Yankee Stadium. This slate offers a balanced mix of safe picks and value. Always check current odds, but our picks above reflect the smartest wagers for today.

Q: What are the MLB picks for today (April 26)?
A: We’ve broken down each game. Generally, the picks lean heavily toward teams with superior pitching or run support. Favorites we like: Yankees, Tigers, Guardians, Twins, Cardinals, Reds, Mets, Cubs, Giants, A’s, Astros, Diamondbacks, Padres, Dodgers, Mariners, plus Red Sox on the second half of their DH. Use this as a guide for strong MLB predictions today – focusing on pitching matchups and recent form is key.

Q: Which player props stand out in MLB today’s games?
A: Our Top Prop selections target sluggers and consistent hitters. For example, watch Aaron Judge (Yankees), Rafael Devers (Red Sox), Yordan Álvarez (Astros), Fernando Tatis Jr. (Padres), Mookie Betts (Dodgers), and Julio Rodríguez (Mariners) for long balls or RBI chances. On the value side, props like Riley Greene or Spencer Torkelson (Tigers) offer upside. These reflect the best MLB player props today, focusing on players in favorable matchups and recent hot form.

Q: How do I find reliable MLB predictions today?
A: The best MLB predictions combine statistical analysis with current trends. Pay attention to starting pitchers (ERAs, recent starts), team offense (runs scored recently), home/road splits, and injuries. Resources that aggregate betting odds and lineups can help. Our MLB predictions today are built on these factors – for instance, we see Mets/Nationals and Dodgers/Pirates as near-certainties due to elite pitching and offense disparities.

Q: What are the overall best bets today?
A: Beyond individual games, watch the two doubleheader closers: Tigers and Red Sox should each take both games. Focus on moneylines for teams with elite aces (e.g. Dodgers, Mets, Yankees) and on totals where matchups suggest a blowout or extra runs (like Reds-Rockies over 10). These represent our best bets today across the MLB slate, balancing favorites and judicious overs where appropriate.

Q: Where can I find the best MLB player props today?
A: Look at high-leverage hitters facing weaker pitchers or in hitter-friendly parks. For April 26, players like Aaron Judge (+200 to HR), Fernando Tatis Jr. (+280 to HR), and Julio Rodríguez (+365 to HR) are strong candidates. Websites of major sportsbooks and prop specialists list updated odds. Use our MLB player props today suggestions as a starting point, focusing on star batters in the lineup on offense-heavy days.